ChloroquineV1, France, Analysis, bibRecord, 000234

[A new hope against malaria: The contribution of organometallic chemistry]

Identifieur interne : 000234 ( France/Analysis ); précédent : 000233; suivant : 000235

[A new hope against malaria: The contribution of organometallic chemistry]

Auteurs : Christophe Biot [France] ; Daniel Dive [France]

Source :

RBID : Hal:hal-00641812

Descripteurs français

mix :
- Paludisme, candidat médicament, ferroquine, mécanisme d’action, résistance.

English descriptors

mix :
- Malaria, drug candidate, ferroquine, mechanism of action, resistance.

Abstract

Emblem of bioorganometallics, ferroquine is the most advanced organometallic drug candidate and about to complete phase II clinical trials as a treatment for uncomplicated malaria. This ferrocene-containing compound is active against both susceptible and resistant Plasmodium falciparum and Plasmodium vivax strains and/or isolates to the most used drug, chloroquine. This article sums up the discovery of ferroquine, its antimalarial activity, the hypothesis of its mode of action and the current absence of resistance in vitro.

Url:

https://hal.archives-ouvertes.fr/hal-00641812

Affiliations:

France

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000250
to stream Hal, to step Curation: 000250
to stream Hal, to step Checkpoint: 000168
to stream Main, to step Merge: 001462
to stream Main, to step Curation: 001460
to stream Main, to step Exploration: 001460
to stream France, to step Extraction: 000234

Links to Exploration step

Hal:hal-00641812

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en">[A new hope against malaria: The contribution of organometallic chemistry]</title>
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<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>Malaria</term>
<term>drug candidate</term>
<term>ferroquine</term>
<term>mechanism of action</term>
<term>resistance</term>
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<keywords scheme="mix" xml:lang="fr"><term>Paludisme</term>
<term>candidat médicament</term>
<term>ferroquine</term>
<term>mécanisme d’action</term>
<term>résistance</term>
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<front><div type="abstract" xml:lang="en">              <p>Emblem of bioorganometallics, ferroquine is the most advanced organometallic drug candidate and about to complete phase II clinical trials as a treatment for uncomplicated malaria. This ferrocene-containing compound is active against both susceptible and resistant Plasmodium falciparum and Plasmodium vivax strains and/or isolates to the most used drug, chloroquine. This article sums up the discovery of ferroquine, its antimalarial activity, the hypothesis of its mode of action and the current absence of resistance in vitro.</p>
            </div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
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<tree><country name="France"><noRegion><name sortKey="Biot, Christophe" sort="Biot, Christophe" uniqKey="Biot C" first="Christophe" last="Biot">Christophe Biot</name>
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<name sortKey="Dive, Daniel" sort="Dive, Daniel" uniqKey="Dive D" first="Daniel" last="Dive">Daniel Dive</name>
</country>
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Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/France/Analysis

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000234 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000234 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    France
   |étape=   Analysis
   |type=    RBID
   |clé=     Hal:hal-00641812
   |texte=   [A new hope against malaria: The contribution of organometallic chemistry]
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

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Serveur d'exploration Chloroquine

[A new hope against malaria: The contribution of organometallic chemistry]

[A new hope against malaria: The contribution of organometallic chemistry]

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri